Thermosensitive Nanogels is Lower Than the Critical Solution Temperature, Hydrogen Bonds Are Formed Between Water and Hydrophilic Groups, and the Nanogels Are in a Swollen State. When the Temperature is Above the Critical Solution Temperature, the Hydrophobic Interaction Between the Hydrophobic Groups Dominates, and the Three-dimensional Structure of the Nanogel is Destroyed and Dissolved. The Researchers Prepared Temperature-sensitive Nanogels Based on Polyisopropylacrylamide Co-acrylic Acid Polyvinyl Caprolactam an.
These Nanogels Can Release Drugs at Specific Temperatures to Achieve Precise Treatment. Sensitive Nanogels Sensitive Nanogels Contain Oman Email List Anionic or Cationic Groups in Their Can Be Protonated or Deprotonated. Anionic Groups Include Carboxylic Acid Groups or Sulfonic Acid Groups, While Cationic Groups Usually Have Terminal Amino Groups. When the Environment Changes, the Ratio of Different Ionic States of These Groups Will Change, Which Will Lead to Changes in Hydrophilicity and Ultimately Change the The Three-dimensional Network Structure of the Gel.
The Values of Healthy Tissue Stomach and Tumor Tissue Are Different, So the Response of Nanogels to Different Values can Release the Contained Drugs at Specific Locations. Photosensitive Nanogels the Three-dimensional Structure of Photosensitive Nanogels Generally Contains Photosensitive Groups. Common Photosensitive Groups Include Argon Benzospiropyran O-nitrobenzylphenyl Methyl Ester and Coumarin Ester. When the Photosensitive Nanogel is Stimulated by Light, the Internal Photosensitive Groups Will Isomerize or Photodegrade, and the Gel Structure and Morphology Will Also Change, Thereby Releasing the Contained Drugs to Achieve the Desired Therapeutic Effect. There Are Also Photosensitive Nanogels Containing Metal Particles.